Finding the cause and extent of liver damage is important in guiding treatment. Your doctor is likely to start with a health history and thorough physical examination.

Your doctor may then recommend:

Blood tests. A group of blood tests called liver function tests can be used to diagnose liver disease. Other blood tests can be done to look for specific liver problems or genetic conditions.

Imaging tests. An ultrasound, CT scan and MRI can show liver damage.

Checking a tissue sample. Removing a tissue sample (biopsy) from your liver may help diagnose liver disease and look for signs of liver damage. A liver biopsy is most often done using a long needle inserted through the skin to extract a tissue sample that’s sent to a lab for testing.